Your PICO should help you choose keywords and key phrases for your search. If you combine these with the AND operator your results should include ALL the terms (see Search Operators). Many databases allow you to search for keywords one at a time, and then combine the search sets later, using your Search History. This is the best way to search if you are using a thesaurus such as CINAHL Headings or MeSH (Medical Subject Headings).
For each concept that you identify, consider using synonyms (alternative terms) including alternative spelling. You can combine these using the OR operator (see Search Operators.)
Consider searching in a selected field(s), such as title or subject. Searching using CINAHL Headings or MeSH is the most advanced way to do this.
Consider limiters that will restrict your search, such as language, date of publication, type of study, age group etc. You can apply these either as part of your search, or to your search results. The specialised health & medicine databases usually have specialised limiters.
CSU Library has a general guide to Database Help.
You can also get help from the Help sections within databases. For example:
Charles Sturt University acknowledges the traditional custodians of the lands on which its campuses are located, paying respect to Elders, both past and present, and extend that respect to all First Nations Peoples.
Charles Sturt University is an Australian University, TEQSA Provider Identification: PRV12018. CRICOS Provider: 00005F.